[{"reviewer_name":"Kelsey Heenan","review_text":"\"Not only did I see my biomarkers improve, I know I\u2019m taking exactly what my body needs for better performance and better day to day life.\"","reviewer_image":"https:\/\/dev2.choosejoi.co\/wp-content\/uploads\/2024\/03\/Kelsey-H-headshot-1-e1711499030467.jpg"},{"reviewer_name":"Janna Breslin","review_text":"\"I need to be in tune with my body and Joi offers deep dive blood diagnostic labs that allow me to supplement with precision through Smart Supps.\"","reviewer_image":"https:\/\/dev2.choosejoi.co\/wp-content\/uploads\/2024\/03\/Screenshot-2024-03-26-172513.png"},{"reviewer_name":"Jessica Cooper","review_text":"\"The process with Joi was super easy and customized to fit my needs. I\u2019m busy with 3 kids, a husband and a full-time job so feeling my best and having energy is a must for me!\"","reviewer_image":"https:\/\/dev2.choosejoi.co\/wp-content\/uploads\/2024\/03\/jessica.jpg"}]
Rapamycin
Rapamycin
- 12 capsules/bottle
Rapamycin is considered to be one of the most promising healthspan-promoting therapies for its role in slowing down the formation of senescent cells through its inhibition of the mTOR complex I pathway.
Taken in small doses over an extended period of time, Rapamycin supports processes that preserve cellular health with age, leading to a longer period of life spent active and with less dysfunction. *All prescription products require a medical consultation with a licensed provider, either asynchronously or synchronously, who will determine if a prescription is appropriate. If not deemed appropriate, you will be immediately refunded. Get Started:
Joi drugs may include compounded products that have not been approved by the FDA.The FDA does not verify the safety or effectiveness of compounded drugs including compounded Rapamycin. Joi specialists may prescribe this medication off label from its intended use.Read More
Potential Benefits
Promote a longer and healthier lifespan
Improve metabolic health
Strengthen immune function
Help boost overall energy levels
Improve skin health
What's Included?
Board Certified Clinicians
Lifestyle & Nutrition Support
Unlimited Messaging
1:1 Coaching
Doctor Prescribed Medications
Access to Labs & Supplements
FAQs
What is sirolimus?
We prescribe sirolimus because it is more bioavailable than the compounded version of rapamycin.
What is the rapamycin anti-aging protocol?
Generally, 5mg capsules taken once a week orally. New patients will be titrated up by clinician guidance. Providers may also cycle patients off for a short period of time.
Do I need labs to be on treatment?
We require a lab to start and then after 3 months of treatment. After that we test annually.
What are the side effects?
Possible side effects include sore or inflamed mouth, weakened immune system, anemia or fatigue, constipation or diarrhea, elevated lipid levels, high blood pressure, swollen hands or feet. Please contact us on the onset of any symptom you think may be related to treatment.
What is autophagy?
Rapamycin directly stimulates the cellular cleaning process known as autophagy, effectively clearing toxic debris and promoting cellular rejuvenation.
What is cellular senescence?
Cellular senescence is a process that results from a variety of stresses and leads to a state of irreversible growth arrest. Senescent cells accumulate during aging and have been implicated in promoting a variety of age-related diseases.
What is the mTOR pathway?
The mTOR pathway, found in all cells, determines when a cell should grow and divide. However, with time, it can become too active, resulting in unchecked cell growth and compromised tissue health. Rapamycin is a direct inhibitor of the mTOR pathway. Low doses of rapamycin appear to reset mTOR activity to a more youthful state—active when needed and dormant when not required.
Injection site reaction (pain, swelling or redness)
Rash
Difficulty breathing and swelling of the face, mouth, lips or tongue
Headache
Flushing
Difficulty swallowing
Dizziness
Hyperactivity
Sleepiness
Hives
Nausea
Vomiting
Changes in taste
Tightness in the chest
NY & NJ Residents
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NY & NJ Residents
It looks like you are in New York or New Jersey - due to local requirements we have different lab diagnostics pricing in these states. Please close this message to review the revised applicable pricing for your service area.
Behavioral Health Resources
Thank you for choosing us to provide support with your health needs. We want to ensure our patients receive the most appropriate and evidence-based care when working with our team of medical professionals. Unfortunately, the behavioral health history that you have identified is not considered to be best practice when treated through telehealth. When individuals are experiencing conditions that you have identified, since patient safety is paramount, we refer them to a trusted local provider in their immediate area for in-person care for the most beneficial results.
We apologize for any inconvenience this may cause and fully appreciate the opportunity that you have provided us in choosing our service for your care. We have curated this list of resources to assist based on potential needs and/or concerns that were mentioned during your visit.
Crisis/Emergency Resources:
Phone Call:
988 - Crisis Support Lifeline
1-800-273-8255 - National Crisis Support
1-866-488-7386 or text START to 678678. A national 24-hour, toll free confidential suicide hotline for LGBTQ youth.
Text:
Text MHA to 741741 and you will be connected to a trained Crisis Counselor. Crisis Text Line provides free, text-based support 24/7.
Due to regulations beyond our control, we cannot ship testosterone therapy to your state. We can, however, still ship other hormone therapies, including estrogen, progesterone, DHEA, pregnanolone and all peptide therapy.
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